Once a drug is repackaged into another container, as often happens in the pharmacy, the shelf-life could decline due to environmental variations.Studies and case reports are lacking on this topic.Solid dosage forms, such as tablets and capsules, appear to be most stable past their expiration date. Drugs that exist in solution or as a reconstituted suspension, and that require refrigeration (such as amoxicillin suspension), may not have the required potency if used when outdated. Accessed May 29, 2018 at https://elsevierhealth.com/action/get Shared Site Session? Expired Epi Pens May Still Help Save a Life: Study. Drug products marketed in the US typically have an expiration date that extends from 12 to 60 months from the time of manufacturer.
However, it is difficult for any one consumer or health care provider to know which product could have an extended shelf life.For many patients, these questions arise because medications can be expensive and it is costly to frequently replace expired but unused medications.The expiration date is the final day that the manufacturer guarantees the full potency and safety of a medication. pharmaceutical manufacturers are required by law to place expiration dates on prescription products prior to marketing.Drugs that exist in solution, especially injectable drugs, should be discarded if the product forms a precipitant or looks cloudy or discolored. Accessed May 29, 2018 at https://org/sections/health-shots/2017/07/18/537257884/that-drug-expiration-date-may-be-more-myth-than-fact 10. A small evaluation of almost 40 expired, unused Epi Pens gathered from patients showed that the pens retained 80% of their initial dose of epinephrine, some for up to four years past the expiration date on the device. That Drug Expiration Date May Be More Myth Than Fact.